pentobarbital will lower the level or result of mestranol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
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pentobarbital will lower the extent or outcome of fosaprepitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will decrease the level or outcome of rolapitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Extensive-term coadministration of sturdy CYP3A4 inducers with rolapitant may perhaps considerably lower rolapitant efficacy.
pentobarbital will reduce the extent or result of celecoxib by affecting hepatic enzyme CYP2C9/10 metabolism. Minimal/Importance Unknown.
The excretion of unmetabolized barbiturate is a person feature that distinguishes the long-performing classification from Those people belonging to other types which happen to be Pretty much solely metabolized. The inactive metabolites with the barbiturates are excreted as conjugates of glucuronic acid.
Usage of sedative doses for the duration of labor does not impair uterine activity, however, comprehensive anesthetic dose can lower the drive and frequency of uterine contractions.
pentobarbital will lower the extent or influence of cilostazol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
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pentobarbital will reduce the extent or effect of lopinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will lower the level or outcome of acalabrutinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will minimize the level or impact of carvedilol by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Check.
pentobarbital decreases effects of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Coadministration of CYP3A4 inducers may reduce sufentanil degrees and efficacy, probably precipitating withdrawal syndrome in sufferers which have produced Bodily dependence to sufentanil. Discontinuation of concomitantly made use of CYP3A4 inducers might enhance sufentanil plasma focus.